ASK IN 1 - Names and Identifiers
ASK IN 1 - Physico-chemical Properties
Molecular Formula | C23H21N7O
|
Molar Mass | 411.46 |
Density | 1.50±0.1 g/cm3(Predicted) |
Solubility | DMSO: 15.5 mg/mL |
pKa | 11.20±0.70(Predicted) |
Storage Condition | -20℃ |
ASK IN 1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.43 ml | 12.152 ml | 24.304 ml |
5 mM | 0.486 ml | 2.43 ml | 4.861 ml |
10 mM | 0.243 ml | 1.215 ml | 2.43 ml |
5 mM | 0.049 ml | 0.243 ml | 0.486 ml |
Last Update:2024-01-02 23:10:35
ASK IN 1 - Reference Information
biological activity | GS-444217 (ASK1-IN-1) is an effective, selective, an oral inhibitor with ATP competitive ASK1 (apoptosis signal-regulating kinase 1) with an IC50 value of 2.87 nM. |
Target | Value |
ASK1
(Cell-free assay)
| 2.87 nM |
Last Update:2024-04-09 21:32:10